NFL.com reported Mayfield will miss at least three weeks because of a throwing-thumb injury.
FFT fantasy impact9/10
Plan for a multi-week absence and reassess Tampa Bay's passing-game expectations with Mayfield sidelined.
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Nacua has been ruled inactive for the Rams' game against the Giants because of a hip injury.
FFT fantasy impact10/10
Remove Nacua from active lineups for this game and use a confirmed active replacement if your platform still permits a swap.
The Chargers placed Njoku and Kolar on injured reserve, removing two tight ends from the active roster.
FFT fantasy impact8/10
Njoku should be benched or moved to an IR slot where eligible; monitor the Chargers' next depth chart and snap distribution for Gadsden's role.
Goedert's diagnosis is a sprained MCL, and the reporting points to a multi-week absence after his Week 2 exit.
FFT fantasy impact9/10
Plan to replace Goedert for the near term; wait for Philadelphia's practice reports before projecting an exact return date.
Robinson appeared as a limited participant with an ankle injury on Monday's estimated report.
FFT fantasy impact6/10
Treat this as an early monitoring item and wait for Atlanta's actual practice report before changing a Week 3 lineup plan.
Brooks is seeking second opinions after aggravating a groin injury, and the Panthers view him as week to week.
FFT fantasy impact8/10
Bench Brooks until Carolina clarifies his timetable and practice participation; avoid assuming he will be available for Week 3.
Kubiak said Bowers will practice this week, a concrete recovery step after the tight end's knee issue.
FFT fantasy impact7/10
Treat the practice participation as a positive availability signal, not a final clearance. Follow the week’s practice designations before locking Bowers into a lineup.
Schefter reported that Reed suffered a back injury Sunday and that Green Bay is still determining treatment and recovery timing.
FFT fantasy impact8/10
Reed's Week 3 outlook is unsettled until Green Bay provides a practice status or timetable. Keep a contingency option available rather than assuming the injury is minor.
Goedert left Philadelphia's Week 2 win over Tennessee in the second quarter and did not return. RotoWire NFL, citing Ian Rapoport, reports that he is scheduled for a Monday knee MRI. The result and the Eagles' practice reports will determine his Week 3 outlook.
FFT fantasy impact7/10
Treat Goedert as a Week 3 availability watch rather than making a lineup decision before the MRI and Philadelphia's practice reports provide a clearer timeline.
Pierce did not return after a left-heel injury, but Indianapolis reported negative X-rays. His practice status will determine whether he is available next week.
FFT fantasy impact7/10
Monitor Indianapolis' first practice report rather than assuming the negative X-rays clear Pierce for next week.
Williams was ruled out after a right hamstring injury in the fourth quarter of Chicago's loss to Minnesota. His severity and Week 3 availability remain unconfirmed.
FFT fantasy impact8/10
Hold off on lineup decisions until Chicago releases imaging results or a practice designation.
Price's initial chest X-rays were negative after he left Sunday's game. Seattle still has additional testing planned, so his Week 3 availability is unresolved.
FFT fantasy impact6/10
Treat the negative X-rays as encouraging, not a clearance; monitor Seattle's medical update and practice report.
Minnesota placed Mason on injured reserve after he suffered a thumb injury in Week 1. He will miss at least four games under NFL injured-reserve rules, removing a back who led the Vikings with 15 carries and 59 rushing yards in the opener.
FFT fantasy impact9/10
Move Mason to an IR slot where available; Aaron Jones Sr. has the clearest path to a larger share of Minnesota's backfield work while the team replaces depth.
Cooper's MRI produced encouraging results after his Week 1 ankle sprain, but the Jets receiver remains week to week and could miss time. The report's hoped-for return window is within four weeks rather than a confirmed Week 2 availability.
FFT fantasy impact6/10
Do not count on Cooper for Week 2 until the Jets provide practice participation or a game-status update.
Murray did not return after Minnesota evaluated him for a concussion. The team has not announced a diagnosis beyond the in-game evaluation or a Week 2 timetable.
FFT fantasy impact8/10
Plan for Murray's Week 2 status to remain unsettled until Minnesota issues a postgame or practice update; do not assume the in-game ruling establishes the length of any absence.
Flowers was ruled out after leaving the Colts game. Severity and a recovery timetable have not been reported.
FFT fantasy impact8/10
Treat Flowers as a Week 2 availability question until Baltimore supplies a postgame update; do not infer a timeline from the in-game designation.
Sampson did not return after a knee injury. No diagnosis or expected absence beyond this game has been reported.
FFT fantasy impact7/10
Monitor Cleveland's postgame report before making waiver or lineup changes; the in-game ruling alone does not establish a multiweek absence.
San Francisco has ruled out an Achilles injury for Stribling, but the team has not yet established the severity or timetable for his ankle issue.
FFT fantasy impact6/10
Do not treat the intact Achilles as clearance. Deep-league managers should monitor San Francisco's next injury report before relying on Stribling or making a waiver move.
Brown is expected to be sidelined at least four weeks after MRI confirmation of a high ankle sprain. The reported timetable makes him an immediate lineup absence rather than a week-to-week decision.
FFT fantasy impact9/10
Plan for Brown to be unavailable through at least the next month and use a rostered replacement in the short term. Watch New England's practice reports and transaction decisions for any formal IR move or revised return target.
NFL Network reports that Darnold is expected to miss Seattle's Week 2 game at Arizona after his hip injury in the opener; Mike Macdonald characterized the injury as a muscle issue.
FFT fantasy impact9/10
Plan for Darnold to be unavailable in Week 2 unless Seattle changes course; Drew Lock becomes the short-term starter in a two-quarterback or superflex contingency.
Schefter and Rapoport reported that Bowers had a meniscus trim Tuesday after a knee injury was diagnosed last week. The report projects a short absence, but it puts the Raiders' primary tight end out of the immediate Week 1 outlook.
FFT fantasy impact9/10
Remove Bowers from the short-term starting plan and watch the Raiders' final practice and game-status reporting before treating the one-to-two-game estimate as a firm return date.
Odunze was not present for Chicago's Monday practice because of a leg injury, according to a report attributed to Courtney Cronin. The absence establishes a Week 1 monitoring point but does not supply a diagnosis or game-status decision.
FFT fantasy impact7/10
Monitor the Bears' next practice report before locking Odunze into Week 1 lineups; avoid assuming either a lengthy absence or a target redistribution from this single practice note.
Kittle is expected to return to practice Monday as the 49ers prepare for Week 1 in Australia, according to a report attributed to Matt Barrows. The update is a positive recovery signal, but it is not yet an official game-status designation.
FFT fantasy impact7/10
Keep Kittle active in Week 1 planning if he practices as expected, while monitoring the 49ers' official practice and game-status updates for confirmation.
Robinson left a Bears-Titans joint practice after a hit and is being evaluated for a concussion, according to Tennessee coach Robert Saleh. The report did not confirm a concussion diagnosis, protocol entry, or a Week 1 absence.
FFT fantasy impact6/10
Monitor Tennessee's next injury report for a diagnosis and practice status. Do not project a missed game from an evaluation alone.