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Colts coach Shane Steichen said Pierce is on track to play against Baltimore after the wide receiver's ankle issue. The update supports his availability for the opener, though it does not clarify whether his workload will be limited.
Pierce can remain in Week 1 consideration for deeper formats; check the final injury report and game status before treating his role as fully unchanged.
Pierce's activation from PUP is a meaningful recovery step after his ankle surgery and preserves his chance to be ready for the opener. It does not confirm full practice participation or a Week 1 role.
Pierce moves from a long-term availability concern to a Week 1 monitor. Watch for his first practice participation and any Colts workload guidance.
Kittle can now resume practice after the 49ers activated him from PUP. This is a positive availability step, but it does not confirm he will play in Week 1 following his Achilles recovery.
Treat the activation as encouraging, while waiting for practice participation and a Week 1 decision before fully removing availability risk.
